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Microneedling Comparison Chart: Dr. Pen vs Hydra Pen vs BIO Pen

Not sure which Dr. Pen model is right for you? This complete comparison guide breaks down Dr. Pen, Hydra Pen, and BIO Pen devices by cartridge compatibility, speed, battery, wireless design, and key features to help you choose the best option for facial microneedling, serum infusion, or scalp care.

·6 min read
2026 microneedling comparison chart

With so many models available, choosing the right device can feel confusing at first. Many shoppers are not just comparing one pen to another. They are trying to understand the real difference between Dr. Pen, Hydra Pen, and BIO Pen, and which series best matches their routine, goals, and experience level.

This guide is designed to make that decision easier. Instead of looking at model names only, you can compare devices by what matters most: cartridge compatibility, speed levels, battery type, wireless convenience, display screen, and special functions. Whether you are looking for a classic microneedling device, a serum infusion tool, or a model focused on hair and scalp routines, this chart gives you a faster way to identify the right fit.

To help you quickly distinguish the three main series, here is the simplest way to think about them:

Quick Series Overview

Dr.Pen → Microneedling Skincare

Best for general microneedling routines, broader model selection, and versatile feature combinations for face-focused skincare use.

Hydra → Serum Infusion

Best for users who want serum infusion functionality and a more hydration-focused treatment style within the Hydra lineup.

BIO → Hair & Scalp Care

Best for users looking at scalp-focused routines and multifunction-style options designed around hair and scalp care.

Feature Group Dr.Pen Series BIO Pen Series Hydra Pen Series
Feature / Model M9 A11 M8S M8 M7S M7 M5 A10 A9 A8S A7 A6S A6 A1 X5 N2 E30 A20 Q2 Q1S H6 H5 H3 H2
Series Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen Dr.Pen BIO Pen BIO Pen Hydra Pen Hydra Pen Hydra Pen Hydra Pen
Best For ⭐ 2026 Best Seller Pro Model ⭐ Best Seller 2024 Best Seller M7 Upgrade Balanced Comfort Affordable Dual-Use Wireless Starter Long Battery Full Metal Wired Only Classic Travel Beast MTS + PMU Only 3.0mm Pen Pro Basic 1st Model Dual-Use Value High-End Pro Elite Model Smart BIO Firming Hydra Infusion Pro Upgrade Serum Infusion Hydra Starter Basic Infusion Classic
Cartridge Types 18/36/42/NanoR 12/18/24/36/42/NanoR/NanoS 12/18/24/36/42/NanoR/NanoS 11/16/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 11/16/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 9/12/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 9/12/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 12/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 12/18/24/36/42/NanoR/NanoS 12/18/24/36/42/NanoR/NanoS 9/12/24/36/42/NanoR/NanoS/Nano 3D 11/16/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 9/12/24/36/42/NanoR/NanoS/Nano 3D 9/12/24/36/42/NanoR/NanoS/Nano 3D 9/12/24/36/42/NanoR/NanoS/Nano 3D 9/12/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 9/12/24/36/42/NanoR/NanoS/Nano 3D/Nano 5D 11/16/24/36/42/Nano 9/14/25/Nano 9/14/25/Nano 18/36/42/NanoR/NanoS
Dual-Cartridge Chamber
12/24/36/NanoR/NanoS 12/24/36/NanoR/NanoS 12-Pin 0.25mm / 0.5mm / 1mm / NanoR / NanoS
Disposable Cartridges
Travel Size
Upgraded Motor System
RPM Max 7,700 18,000 16,000 15,000 16,000 14,000 12,000 15,000 15,000 15,500 15,000 18,000 15,000 15,000 16,000 15,000 14,000 7,700 16,000 12,000 11,000
Speed Level 6 6 6 6 6 5 5 5 6 6 Infinitely variable speed 6 5 5/6 5 5 5 6 5 5 6 6 6 4
Adjustable Needle Length Auto
Chargeable Built-in Battery
With two extra rechargeable batteries

With two extra rechargeable batteries
Wireless
Speed Display Screen
Upgraded Cartridge Support
Cartridge Recognition
Serum Container Cartridge
Light Therapy
EMS Microcurrent
Ultra-long Battery
Inductive Base
Protective Case

Note: This comparison table is designed for quick product selection. Features, cartridge compatibility, and included accessories may vary by batch or package version.

This series-first, model-second approach simplifies the decision process. Most shoppers start by identifying their treatment goal, then narrow down to a specific device that matches their needs. Once you know whether you are looking for microneedling skincare, serum infusion, or hair and scalp care, choosing the right model becomes much more straightforward.

Tip: If you’re choosing your first device, start with the series that aligns with your treatment goal. Then compare models based on key features like cartridge compatibility, battery type, speed levels, and overall usability.

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